Maintained by the Federal Reserve Bank of St. Louis, this site contains a number of data sources: FRED (current data), ALFRED (archival), GeoFRED (GIS-enabled), Graphical (FREDGraph), Banking (CASSIDI) and Historical data (FRASER).
The Survey of Industry Research and Development is a collection of data from R&D expenditures and trends in industries all across the U.S. Contains on pre-SIC and SIC code data, which means data up until 1999. More current data are being developed.
International Labor Organization database of labor statistics provides multiple datasets with annual and infra-annual labour market statistics for over 100 indicators and 230 countries, areas and territories.